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cbd psoriasis study

Cannabis for Refractory Psoriasis-High Hopes for a Novel Treatment and a Literature Review

Affiliation

  • 1 Department of Neurosurgery, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. [email protected]
  • PMID: 27164964
  • DOI: 10.2174/1574884711666160511150126

Cannabis for Refractory Psoriasis-High Hopes for a Novel Treatment and a Literature Review

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Authors

Affiliation

  • 1 Department of Neurosurgery, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. [email protected]
  • PMID: 27164964
  • DOI: 10.2174/1574884711666160511150126

Abstract

Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to antipsoriatic armamentarium.

Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interact …

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

Affiliation

  • 1 Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena – Second Opinion Medical Network, Modena (MO), Italy.
  • PMID: 30993303
  • DOI: 10.7417/CT.2019.2116

Free article

A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

  • Search in PubMed
  • Search in NLM Catalog
  • Add to Search

Authors

Affiliation

  • 1 Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena – Second Opinion Medical Network, Modena (MO), Italy.
  • PMID: 30993303
  • DOI: 10.7417/CT.2019.2116

Abstract

Objective: To investigate the therapeutic effect of CBD-ointment administered on severe skin chronic diseases and/or on their outcome scars.

Methods: A spontaneous, anecdotal, retrospective study of 20 patients with two most frequent skin disorders: psoriasis (n: 5 patients), atopic dermatitis (n: 5) and resulting outcome scars (n: 10). The subjects were instructed to administer topical CBD-enriched ointment to lesioned skin areas twice daily for three months treatment.

Results: Based on skin evaluations (hydration, TEWL, elasticity), clinical questionnaires (SCORAD, ADI, PASI), and supported by photographic data and investigators’ clinical assessment, the results showed that topical treatment with CBD-enriched ointment significantly improved the skin parameters, the symptoms and also the PASI index score. No irritant or allergic reactions were documented during the period treatment.

Conclusions: The topical administration of CBD ointment, without any THC, is a safe and effective non-invasive alternative for improve the quality of life in patients with some skin disorders, especially on inflammatory background.

Keywords: CBD; Ointment; Quality of life; Skin.

The topical administration of CBD ointment, without any THC, is a safe and effective non-invasive alternative for improve the quality of life in patients with some skin disorders, especially on inflammatory background.