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Should You Try CBD or Cannabis Creams for Pain Relief?

Cannabis-infused sports creams claim to offer muscle relief. We spoke to experts to see if they’re worth a shot.

Chances are, you’re no stranger to muscle aches. Well, what if we told you that cannabis creams might help provide relief?

Yes, there’s a new(ish) type of topical ointment on the market, and it’s infused with cannabidiol (CBD) from marijuana. Manufacturers claim it can help alleviate acute pain and muscle soreness. CBD is similar to THC, except it’s non-psychoactive, meaning some researchers view it as the golden child of medicinal use.

Science has confirmed that cannabis is an effective pain reliever, reinforced in a massive new report from the National Academies of Sciences, Engineering, and Medicine. But there’s a big difference between ingesting cannabis or its individual chemicals orally and absorbing it through your skin. Here, the lowdown on this new crop (no pun intended) of pain relievers.

What Exactly Is a CBD-Infused Topical Cream?

The ointment is made from infusing high-quality cannabis flowers in some kind of quality oil-coconut or olive typically-which extracts the active compounds, either CBD, THC, or both depending on the type of hemp used. (Here’s a guide to the difference between THC, CBD, cannabis, and hemp.) This oil is then blended with other therapeutic herbs, like arnica or lemongrass essential oils, that are well-known pain relievers.

If you read the ingredient list, often everything in the jar is straight from mother earth. As long as that’s indeed the case with the cream you have your eye on, the formula is immensely safe, chemically, says Gregory Gerdeman, Ph.D., neurophysiologist who researches cannabinoid biology and pharmacology at Eckerd College in Saint Petersburg, FL. And since they’re formulated to be topical (absorbing into the top layer of skin) and not transdermal (which would pass through the skin and into your bloodstream) there’s no risk of getting high, explains Gerdeman. (P.S. Here’s How Marijuana Affects Athletic Performance.)

“When it comes to cannabis-based topicals for muscle soreness or other pain relief, there’s absolutely no reason why it should be a big deal to try,” he says.

They may be safe, but there’s one massive problem: There’s practically no scientific data to support the idea that a CBD-infused topical cream is any more effective than other topical pain relievers, like Tiger Balm, BenGay, or Icy Hot. Michelle Sexton, a San Diego-based naturopathic doctor and medical research director of the Center for the Study of Cannabis and Social Policy says that her patients do seem to have a great interest in CBD ointments, and roughly 40 percent of them have indeed tried one. However, these people are in her office now because the topicals didn’t work for them. “As a medical professional, my opinion is there’s little evidence to back up the claims being made—it’s all marketing for now,” she says.

How CBD and Cannabis Pain-Relief Creams Work

There is an argument to be made for the simple fact that science hasn’t caught up to the trend (and laws) of cannabis yet. (Here’s what research has to say about the potential benefits of CBD and cannabis so far.) And there are doubtlessly researchers testing the efficacy of CBD creams for pain relief as we speak.

The theoretical logic is there, Gerdeman says. What, exactly, is that thinking? Well, there are a few different ways CBD could help regulate pain—by increasing your natural endocannabinoids, decreasing your inflammatory response, and desensitizing your pain receptors (although it’s still unclear whether this stands when absorbed topically compared to orally).

Let’s start simple: Endocannabinoids are natural signals in your body that help maintain homeostasis by detecting and regulating hunger, pain, mood, and memory. (They’re actually part of your post-workout exercise high.) CBD helps elevate your natural levels of pain-relieving endocannabinoids by blocking metabolism as they’re moving around your body.

The second method of pain relief centers around the damage you do when you work out. When you strength train, you create micro-tears in your muscles, which is why you feel sore as you heal. Once your immune cells detect damage, they release inflammatory mediators in order to repair the tissue. CBD, though has the ability to limit the release of some proinflammatory signals, thereby helping with pain without thwarting the healing entirely, Gerdeman explains.

Finally, you have receptors called TrpV1 that detect and regulate your body temperature. When activated, they put out heat, soothing your pain receptors. Using this channel, CBD makes these pain receptors hyperactive for a period of time, causing them to get hot, desensitizing them and downregulating those pain-sensing nerve endings.

What Science Says About CBD Creams

Phew—enough of that biology lesson. The real problem here is that all of this has yet to be proven in scientific studies on humans.

A study analysis in Journal of Pain Research confirms that topical use of certain cannabinoid topicals can reduce pain in animals with inflammation or neuropathic pain. And science has found topical creams with THC and CBD help relieve pain for conditions like multiple sclerosis. But for the vast majority of chronic pain—and most certainly for acute pain like post-workout—the scientific jury is 100 percent still out. “There’s a little bit of data in support of CBD for pain relief, but to go from animal to human is a giant leap,” Sexton says.

“The pain and stiffness that comes post-workout or from overexertion certainly has a pro-inflammatory component to it, so it’s reasonable to think CBD or other cannabinoids might have benefits, but we have no research to support this yet,” Gerdeman adds.

The other issue? Topical CBD and cannabis creams will treat anatomical structures within 1 centimeter of the skin—and the muscle where your actual soreness is located is going to be deeper than that, explains Ricardo Colberg, M.D., a physician at Andrews Sports Medicine and Orthopaedic Center in Birmingham, AL. (The good news: Since it doesn’t need to be absorbed deeply, CBD and cannabis could do amazing things as a skincare ingredient.)

The fatty tissue can only hold so much oil, so, theoretically, if you apply enough of a CBD cream to your skin, it might leak down into your skeletal muscle just out of diffusion, Sexton adds. But there’s no study to show this, and that means you’re going to be rubbing on a whole lot of the stuff.

This takes us to the next problem: There is no regulation around how much active CBD or THC is in each cream or how much of the compound is needed to see relief. Read: “If you have three products that say 1 percent CBD infused in coconut oil, one could be great and the other two could be crap—that’s the reality of cannabis medicine right now,” Gerdeman says. (See: How to Buy Safe and Effective CBD Products)

So. Should I Try It?

That’s not to say CBD creams definitely won’t reduce your acute pain or muscle soreness. That’s because pretty much all of these creams on the market right now have other scientifically-proven analgesic compounds, like menthol, camphor, and capsaicin which are also found in other, non-CBD topical pain relievers. “Any cream with a heating or cooling sensation desensitizes the nerves to pain by distracting them with stimuli on top,” Dr. Colberg explains. Plus you’re often massaging the area as you apply, which improves circulation and reduces muscle spasms, he adds. (Get the best of both worlds by trying a CBD massage.)

So do you need the CBD? All our experts agree that until we have more peer-reviewed research, all claims are marketing hype and not evidence-based. (Or, they can be anecdotal. Read what happened when one woman tried CBD for anxiety.)

But there is an argument to be made for simply believing the CBD adds that special something. “Scientific literature says there’s a 33 percent chance of the placebo effect helping people, so for some, just using a cream they believe can help will provide some relief,” Dr. Colberg adds.

The short of it: Science hasn’t confirmed creams with CBD will have any greater benefit than those without, but there’s little-to-no risk in trying it out (other than wasting your money, of course). And if you believe in the power of CBD-infused creams, that may be enough to score some relief. (Consider trying these: Products That Personal Trainers Use to Relieve Muscle Soreness)

Cannabis-infused sports creams and CBD creams and rubs claim to offer muscle relief. But do they really work? Here's what you need to know about cannabis and CBD creams for pain.

CBD Vs Icy Hot: Should You Give CBD A Try?

Most people suffer muscle aches at some time or another. The common way of easing the pain is to use a topical ointment, like Icy Hot. But recently, cannabis creams are getting the hype on the market.

This new type of topical ointment contains cannabidiol (CBD) from the cannabis plant. It promises to help reduce acute pain and muscle aches. Unlike THC, CBD is non-psychoactive which means that it won’t get you high.

According to science, cannabis is a good pain reliever. However, results may vary depending on how you use it. Here are the facts about this new pain relief medication and how it compares with Icy Hot.

What Is A CBD-Based Topical Cream?

This new topical cream is made from steeping cannabis flowers in some type of oil- coconut or olive. Active compounds (THC, CBD, or both), are then extracted and then combined with other therapeutic ingredients, like arnica or other essential oils.

If you check the ingredients list, almost everything is natural. This means that formula is safe to use. And since they’re made to be absorbed on the top layer of the skin and not your bloodstream, there’s no chance of getting high.

Although this type of topical is safe, there’s one big issue: There’s no scientific evidence to prove that cannabis-based creams are more effective than normal topical creams, like Icy Hot. At this moment, this cannabis-infused topical cream is all marketing.

How A CBD-Infused Cream Works

Although science and laws haven’t caught up with the fad yet, many researchers are testing the effectiveness of the cream to relieve pain. CBD could help control the pain in a couple of ways, such as:

  • Raising the natural endocannabinoids
  • Reducing inflammatory response
  • Desensitizing pain receptors

Endocannabinoids are neurotransmitters that help maintain the internal balance of the body. They can recognize and control your hunger, pain, and memory. CBD blocks metabolism to increase your pain-relieving endocannabinoid levels.

Another way of relieving pain focus on the damage you endure after working out. During strength training, the muscles are torn causing muscle sores. CBD has the ability to reduce the release of certain proinflammatory signals, hence lessening the pain.

Finally, CBD has the ability to activate the TrpV1 pain receptors. These receptors determine and control your body temperature. When activated, they get hot and desensitizes those nerve endings that sense the pain.

Scientific Evidence And Issues

The potential of CBD-based topical ointment to relieve pain is promising, but there are no scientific studies on humans to support this claim yet.

A study published in the Journal of Pain Research verifies that cannabinoid topicals can minimize inflammation-related pain in animals. Science also discovered that THC- and CBD-based topical cream can reduce the pain for certain medical conditions, like multiple sclerosis.

However, there’s little data to support the claim that CBD is effective in relieving chronic pain and acute pain, like post-workout. The pain that results after a workout has pro-inflammatory component so it’s logical to think that CBD gives relief, but no research has proven this claim yet.

Another concern about topical creams is their inability to treat soreness on the muscles that are located deep within. In general, topical creams only reaches within 1 centimeter of the skin.

You also need to rub a lot of the cream because the fatty tissue has a limit in holding the oil. Out of diffusion, some of the creams might perforate down to your skeletal muscle. Again, no study has confirmed this yet.

This takes us the next issue: There’s no rule around the exact amount of active CBD or THC is in every cream or the amount of the compound required to experience relief. So, you can’t be sure whether all CBD-infused topical creams are great.

Should You Try It?

Although there’s a lack of scientific evidence to prove the effectiveness of CBD-infused creams, it’s still worth giving it a shot. Some of these creams have infused other scientifically-proven analgesic compounds to give pain relief.

Any cream that feels warm and cold desensitizes the nerves to pain. Plus, massaging the affected area enhances circulation and minimizes muscle spasms. There’s no health risk involved in using CBD-infused creams so you can give them a try.

How To Buy CBD-Infused Creams

Before buying any CBD-infused topical cream, check the laws of your state. If it has legalized the use of CBD and THC, look for a compound with a ratio of 1:1. Look for beta-caryophyllene in the ingredient list because they give better results.

Here is a completely legal one that uses CBD derived from Hemp Oil.

If you live in a state that bans the use of THC, choose creams that only use CBD. Look for additional ingredients, like camphor, lemongrass, or menthol. Since there’s no standardized testing on this product, buy from trusted brands.

CBD Vs Icy Hot: Should You Give CBD A Try? Most people suffer muscle aches at some time or another. The common way of easing the pain is to use a topical ointment, like Icy Hot. But recently,